Achievements
- Founded dNovo in 2018 with Y Combinator Summer batch support
- Pioneered direct reprogramming of skin cells into neural stem cells, successfully integrating into a mouse brain
- Published research in top-tier journals like Nature, Cell Stem Cell, and PNAS
- Holds a Ph.D. in Genetics from Stanford University and did postdoc work at Harvard Medical School
- Discovered a safe, personalized method to convert patient skin cells into hair stem cells without passing through pluripotent stage
- Received awards from NSF, Ford Foundation, and California Institute for Regenerative Medicine
Have you met Ernesto Lujan
Ight, so here’s the deal with Ernesto Lujan. This guy is the real deal in biotech startup land. He’s a YC alum from the S18 batch, basically, he crushed it early on. But his story? It’s way more than just another founder chasing a quick buck. It’s about someone genuinely trying to change lives.
So, Ernesto’s background is deep. He’s got a Ph.D. in Genetics from Stanford, which is no joke. After that, he did postdoc work at Harvard Medical School, the kind of place that pushes you to the edge of science. While there, he started messing around with some wild ideas around regenerative medicine and cellular reprogramming. You know, all that sci-fi stuff about turning one cell type into another? Yeah, he was pioneering that.
And get this, he’s published in Nature, Cell Stem Cell, PNAS. That’s top-tier science, no cap. His big breakthrough? He figured out how to directly reprogram skin cells into neural stem cells that could even integrate into a mouse brain. Holy shit, that’s advanced stuff. The guy’s not just about papers; he’s about turning that science into real, tangible tech that actually moves the needle.
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Talk to herFast forward, he spots a problem that’s super personal and relatable: hair loss. Millions suffer from it, and it’s embarrassing as hell. Ernesto’s like, “Let’s fix that with science.” And bam, he starts dNovo in 2018 with Y Combinator’s seed support. The goal? Use his direct reprogramming tech to turn a patient’s own skin cells into hair stem cells, no pluripotent stage, no bullshit. Basically, a personalized, super safe way to regrow hair. That’s a game changer.
What’s crazy is, his process shows he’s not just about science for science’s sake. He’s motivated by real problems, real pain points. He saw hair loss as the perfect target because his tech can actually solve it at the root, literally. Started developing this system during his Harvard days, so he’s been thinking about this for a while.
Bottom line? Ernesto’s not just some scientist in a lab. He’s a guy who took crazy research, saw an everyday problem, and said, “Let’s do something about it.” He’s pushing the boundaries of regenerative medicine, combining hardcore science with real-world impact. The dude’s about changing lives, one hair follicle at a time. That’s why he’s so important.

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