Jacob Borrajo

Jacob Borrajo

Y Combinator Logo Batch: S18

Achievements

  • Founded Amber Bio, pioneering RNA-based gene editing for undruggable genetic diseases
  • Developed Splice Editors, a programmable multi-kilobase RNA editing technology
  • Co-founded Coral Genomics and Scribio to advance genomic measurement tools
  • Holds a PhD in Biological Engineering from MIT, affiliated with the Broad Institute
  • Graduated with a BS in Chemical and Biomolecular Engineering from UCLA
  • Experience includes roles at MIT Media Lab, Harvard Medical School, and Alix Ventures

The lowdown on Jacob Borrajo

Homie, check the vibe on Jacob Borrajo – this dude is the real deal in biotech. He’s a straight-up tech whiz who’s crushed it from the jump. He started out at UCLA, doing Chemical and Biomolecular Engineering, you know, the kind of stuff that’s all about understanding how life actually works at a molecular level. Then, he jumped into grad school at MIT, got his PhD in Biological Engineering, that’s where he really dug into the DNA and gene stuff. Not just that, he was affiliated with the Broad Institute of MIT and Harvard, which is basically the Stanford of biotech research.

This guy’s been everywhere: MIT Media Lab, Harvard Medical School, even at Alix Ventures. Basically, he’s been deep in the trenches of modern science and tech since forever. What’s cool is, he’s not just sitting around doing research, he’s building stuff that actually changes the game. Before Amber Bio, he co-founded Coral Genomics and Scribio, both startups that focused on pushing genomic tech and measurement tools to new levels. Dude’s been about breaking barriers in biotech, no cap.

Now, he’s CEO and Co-Founder of Amber Bio, and man, this is where it gets wild. Amber Bio is all about RNA-based gene editing, a super hot area right now because it’s opening doors to treat diseases that were basically untouchable before, the so-called “undruggable” genetic disorders. Jacob and his team developed this crazy thing called Splice Editors, a programmable multi-kilobase RNA editing tech. Basically, they’re figuring out how to rewrite RNA in ways that can fix genetic issues at a super precise level. That’s some sci-fi shit, but they’re making it real.

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What I love about his story is that it’s about more than just tech for tech’s sake. He’s all about solving huge problems. He’s been in top labs and companies, but his drive runs deeper, pushing the limits of what’s possible to actually help people. He’s relentless, curious as hell, and never shies away from the hardest problems. Starting Coral, Scribio, and now Amber, every move shows he’s in it to make a real impact, not just chase headlines.

Bottom line: Jacob Borrajo is a biotech innovator who’s blending deep science with killer tech to crack genetic diseases wide open. The kind of guy who’s not just playing in the lab, he’s changing the future of medicine. That’s why he’s so important.

Founder ID: 106139

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